Thursday, January 21, 2010

Monday, January 18, 2010

Multiple Sclerosis

It is with disease of the mind, as with those of the body; we are half dead before we understand our disorder, and half cured when we do.
•Affects the central nervous system (CNS; Brain and spinal cord)
•Women affected more then men
Onset of disease- 18-40 yrs. of age
•Patients show relapsing/remitting MS (discrete attacks and recovery periods)
•Secondary progressive MS
•Primary progressive (accumulation of symptoms over time)


“ Multiple scars”

•Autoimmune disorder- Antibodies against self
•Damages the myelin sheath around the nerves
•Demyelination – scarring or plaque formation in CNS
•Nerves loose ability to communicate with each other
•A variety of symptoms seen

Clinical symptoms of MS

•Visual problems ( optic neuritis)
•Muscle weakness
•Tremor, uncoordinated body movement
•Difficulty with coordination and balance
•Impaired speech
•Bladder dysfunction
•Pain, Fatigue
•Emotional instability- depression, mood swings

Causes

•Hereditary factor
•Viruses
•Environmental factors – less sunlight/ Vitamin D
•Chronic cerebro-spinal venous insufficiency
MS is not infectious
Life expectancy of patient same as uninfected person

Treatments available

•There is no cure for MS
•Present drugs to fight against the autoimmunity and manage the symptoms
Corticosteroids (Prednisone)
1.Interferons (Avonex, Betaseron)
2.Copaxone
3.Mitoxantrone
4.Natalizumab
•Physical therapy for muscle strengthening and increasing quality of life
•Symptoms very mild – no medication

Tuesday, January 12, 2010

Multiple sclerosis (MS) is the most common neurological disorder
MS is a disease of the central nervous system (CNS).
The CNS consists of the brain, optic nerves and spinal cord.
This disorder damages the protective insulation (known as "myelin") surrounding the nerves (known as "axons"), and may also damage the nerves within the CNS. As a result, nerve impulses carrying messages from the brain and spinal cord may short circuit, causing reduced or lost bodily function.